Quantitative structure-retention relationship (QSRR) study of retention data of thirteen 5-arylidene-2,4-thiazolidinediones obtained by reversed phase HPTLC. The effect of substituents attached to aryliden ring on the properties of TZD molecule, whose retention is closely correlated to the inhibitory activity, was investigated. PCA was used to show similarities/dissimilarities among the compounds. Stepwise regression models were calculated for each mobile phase modifier used. The obtained models were characterized by good fit and predictive abilities. The descriptors included in the models are connected with both lipophilic and donor/acceptor interactions.
TY - JOUR
AU - Đaković-Sekulić, Tatjana
AU - Lozanov-Crvenković, Zagorka
AU - Rančić, Milica
AU - Trisović, Nemanja
AU - Ušćumlić, Gordana
PY - 2014
UR - https://omorika.sfb.bg.ac.rs/handle/123456789/585
AB - Quantitative structure-retention relationship (QSRR) study of retention data of thirteen 5-arylidene-2,4-thiazolidinediones obtained by reversed phase HPTLC. The effect of substituents attached to aryliden ring on the properties of TZD molecule, whose retention is closely correlated to the inhibitory activity, was investigated. PCA was used to show similarities/dissimilarities among the compounds. Stepwise regression models were calculated for each mobile phase modifier used. The obtained models were characterized by good fit and predictive abilities. The descriptors included in the models are connected with both lipophilic and donor/acceptor interactions.
T2 - Journal of Liquid Chromatography & Related Technologies
T1 - Substituent effects on chromatographic retention data of 5-arylidene-2,4-thiazolidinediones in qsar methodology
EP - 2035
IS - 14
SP - 2021
VL - 37
DO - 10.1080/10826076.2013.825858
UR - conv_1112
ER -
@article{
author = "Đaković-Sekulić, Tatjana and Lozanov-Crvenković, Zagorka and Rančić, Milica and Trisović, Nemanja and Ušćumlić, Gordana",
year = "2014",
abstract = "Quantitative structure-retention relationship (QSRR) study of retention data of thirteen 5-arylidene-2,4-thiazolidinediones obtained by reversed phase HPTLC. The effect of substituents attached to aryliden ring on the properties of TZD molecule, whose retention is closely correlated to the inhibitory activity, was investigated. PCA was used to show similarities/dissimilarities among the compounds. Stepwise regression models were calculated for each mobile phase modifier used. The obtained models were characterized by good fit and predictive abilities. The descriptors included in the models are connected with both lipophilic and donor/acceptor interactions.",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Substituent effects on chromatographic retention data of 5-arylidene-2,4-thiazolidinediones in qsar methodology",
pages = "2035-2021",
number = "14",
volume = "37",
doi = "10.1080/10826076.2013.825858",
url = "conv_1112"
}
Đaković-Sekulić, T., Lozanov-Crvenković, Z., Rančić, M., Trisović, N.,& Ušćumlić, G.. (2014). Substituent effects on chromatographic retention data of 5-arylidene-2,4-thiazolidinediones in qsar methodology. in Journal of Liquid Chromatography & Related Technologies, 37(14), 2021-2035.
https://doi.org/10.1080/10826076.2013.825858
conv_1112
Đaković-Sekulić T, Lozanov-Crvenković Z, Rančić M, Trisović N, Ušćumlić G. Substituent effects on chromatographic retention data of 5-arylidene-2,4-thiazolidinediones in qsar methodology. in Journal of Liquid Chromatography & Related Technologies. 2014;37(14):2021-2035.
doi:10.1080/10826076.2013.825858
conv_1112 .
Đaković-Sekulić, Tatjana, Lozanov-Crvenković, Zagorka, Rančić, Milica, Trisović, Nemanja, Ušćumlić, Gordana, "Substituent effects on chromatographic retention data of 5-arylidene-2,4-thiazolidinediones in qsar methodology" in Journal of Liquid Chromatography & Related Technologies, 37, no. 14 (2014):2021-2035,
https://doi.org/10.1080/10826076.2013.825858 .,
conv_1112 .
